What is the difference between Sildenafil and Tadalafil?

You may have heard these drug names before, but which is right for you? We’ve outlined both drugs, so you can make an informed decision.

Sildenafil

Same Active Ingredient as Viagra™

Activation Time

30 min – 1 hour

Tablet Strength

20mg

Dosage Range

2-5 tablets

Common Starting Dose

2-3 tablets

Price

As low as $1/tablet

Tadalafil

Generic For Cialis™

Activation Time

1-2 hours

Tablet Strength

5mg

Dosage Range

1-2 tablets

Common Starting Dose

1 tablet

Price

As low as $1.50/tablet

Why do some men prefer one medication over the other?

Sildenafil and Tadalafil both have an incredibly high success rate and both deliver the same great results, so which is right for you? At the end of the day, it comes down to personal preference and how you anticipate to utilize the medication. 

Sildenafil

Sildenafil is available in 20mg tablets, with a maximum daily dose 100mg, which is 5 tablets. Generally speaking, Sildenafil has a quicker onset, and is used as an on-demand medication. Higher doses are taken, not more than once a day, right before you’re ready to spring into action. Sildenafil has a shorter half life, meaning it typically stays in your system for up to 4 hours. Sildenafil is a great option for those that know when they will need the medication, and do not want to remember to take a daily pill. Take it when you need it, it’s that easy.

Tadalafil 

Tadalafil is available in smaller doses ranging from 2.5 to 10mg, not to exceed 10mg in a 48 hour period. Tadalafil takes approximately 1-2 hours to kick into action; however, the half life is much higher than Sildenafil, staying active in your system for as long as 36 hours. Tadalafil is a great option for those long, romantic weekends, or simply allowing you to be ready when the mood strikes.

Are ED medications safe for me?

As with any prescription medication, before taking Sildenafil, Tadalafil, or any other ED medication, talk with a physician about possible side effects, drug interactions and in this case, whether you’re healthy enough for sex.

Do not take ED medication if you:

  • Are not healthy enough for sexual activity
  • Have uncontrolled high blood pressure or low blood pressure
  • Take nitrates or alpha-blockers
  • Take riociguat for pulmonary arterial hypertension
  • Are allergic to sildenafil or tadalafil or any of the inactive ingredients in Viagra or Cialis

You should stop using the medication and seek immediate medical help if you experience:

  • Sudden decrease or loss in hearing
  • Sudden vision loss in one or both eyes
  • Chest pain, dizziness, or nausea during sex
  • An erection lasting longer than four hours (priapism)

If you experience side effects while taking Sildenafil or Tadalafil, talk to your doctor right away.